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Serious hypersensitivity reactions, including anaphylactic type reactions, some of which have been life threatening and fatal, reported following parenteral administration of iron dextran products Such reactions have been generally characterized by sudden onset of respiratory difficulty and or cardiovascular collapse; fatal reactions reported following the test dose of iron dextran and have also occurred in situations where test dose was tolerated Administer only in a setting where resuscitation equipment and medications are available; administer test dose prior to first therapeutic dose; observe patients for at least one hour after test dose before administering remainder of initial therapeutic dose During all product administrations, observe patients for signs or symptoms of anaphylactic type reactions Use drug only in patients in whom clinical and laboratory investigations have established an iron deficient state not amenable to oral iron therapy Factors that affect risk for anaphylactic type reactions to iron dextran products are not fully known but limited clinical data suggest risk may be increased among patients with history of drug allergy or multiple drug allergies; additionally, concomitant use of angiotensin converting enzyme inhibitor drugs may increase risk for reactions to an iron dextran product The extent of risk for anaphylactic type reactions following exposure to any specific iron dextran product is unknown and may vary among products; if hypersensitivity reactions occur during administration, stop infusion immediately and manage reaction medically If hypersensitivity reactions occur during administration, stop administration immediately and manage reaction medically buy lasix without a prescription